Thank you for your interest in donating life-saving COVID-19 convalescent plasma. People who have recovered from COVID-19 have antibodies to the virus in their plasma that can help patients still fighting the coronavirus.
Donors must have complete resolution of symptoms at least 14 days prior to donation and submit the pre-registration form below.
If you have recently donated at OneBlood and had an COVID-19 antibody positive test result, we will simply need to verify your record and can get you scheduled to donate convalescent plasma. Call 407-858-4939 to speak with our convalescent plasma team.
If you are a physician or clinician with a potential COVID-19 convalescent plasma donor, please follow our clinician intake path here.
Convalescent plasma (CPP) is plasma collected from people who have recovered from the coronavirus. People who recover from coronavirus infection have developed antibodies to the virus that remain in the plasma portion of their blood. Transfusing the plasma that contains the antibodies into a person still fighting the virus can provide a boost to the patient’s immune system and potentially help them recover.
The experimental treatment is approved by the FDA to be used on an emergency basis and is called “COVID-19 convalescent plasma." Critically ill patients who meet the FDA criteria to receive this therapy can be treated for life-threatening COVID-19.
We are only able to consider COVID-19 convalescent plasma donors that have had a test for COVID-19 (listed above) as eligible to donate COVID-19 convalescent plasma.
You can complete the pre-registration process at oneblood.org/COVID-19 and a donor specialist will contact you will contact you to review your pre-registration information and schedule your donation at a designated location where specially-trained staff and required equipment will be ready to collect your donation. Walk-in COVID-19 convalescent plasma donations at OneBlood donor centers and mobile buses cannot be accepted at this time.
Once your COVID-19 convalescent plasma has been collected, OneBlood transports it to our processing facilities where the unit undergoes additional testing to become the COVID-19 convalescent plasma a patient in need will receive.
It is safe to donate COVID-19 convalescent plasma as collections are done in the same way that thousands of blood donors donate blood products every day.
OneBlood cannot accept more than one patient referral per donor. If you provide more than one patient’s information during your registration, processing will be delayed due to the need to contact you to clarify this policy and update your record to list one patient as the intended recipient of your plasma.
The OneBlood policy for referred donations is to only refer donations to specific patients. Please refer to the OneBlood Policyfor more information.
This is great news! The patient you intended to donate your plasma to may have received plasma earlier for any number of reasons. The plasma that you donated will now be able to be transfused to another COVID-19 patient in need that has a compatible blood type. OneBlood cannot share more information about the destination of your plasma because that is protected patient health information.
Transfusion information is protected patient health information that cannot be shared.
If your first COVID-19 convalescent plasma collection is performed through a standard whole blood collection, you must wait at least 56 days before another collection can be performed. If your first COVID-19 convalescent plasma collection is performed and only plasma is collected, rather than whole blood, you must wait at least 28 days before another collection can be performed. These are waiting periods that are required by the FDA to keep donors safe and able to donate blood products throughout their lives. The potency of additional COVID-19 convalescent plasma donations is unknown at present because there is no widely available method for quantification of antibodies in your collected unit.
All COVID-19 convalescent plasma donors must meet all the required screening criteria for blood donation. This includes questions about your health history and certain behaviors that have been identified as potentially high risk in relation to the safety of transfusing your blood products. In addition to this screening process, all collected blood products, including COVID-19 convalescent plasma undergo rigorous testing to determine the safety of the product before it is released to a hospital for a patient in need. If your donated COVID-19 convalescent plasma tests positive during this testing process, OneBlood has a team of trained staff that will follow up with you to discuss the meaning of your test result and suggested next steps.
Once your pre-registration is complete and a OneBlood staff member has determined you also meet all required screening criteria for blood donation, OneBlood will contact you to schedule your collection time and location. If you have been fully pre-screened and have not been scheduled after 24 hours, please email firstname.lastname@example.org to get in touch with our response team. If you are a clinician looking to schedule a directed donation between a donor and a specific patient, please see our intake process here.
It takes approximately 24 hours to manufacture your donated product and ensure all testing on the product meets FDA requirements. At that point, it will be prepared for shipment to a hospital. More detailed information regarding your donation cannot be provided.
You will be receiving a confirmation letter in the mail from OneBlood regarding your positive COVID-19 antibody test result. Once you receive the letter, please complete the CCP pre-registration process so we can determine your eligibility to become a Convalescent Plasma donor.
If your donation does not meet FDA requirements for safe transfusion to your designated hospital or patient, the physician waiting for that plasma will be notified by a OneBlood representative. OneBlood will notify you when test results require follow up.
The amount of collected plasma does not negatively impact your immune system. Additionally, the required waiting period between donations ensures you maintain adequate antibodies so as not to affect your immune system.
COVID-19 convalescent plasma is plasma collected from people who have recovered from the coronavirus. People who recover from coronavirus infection have developed antibodies to the virus that remain in the plasma portion of their blood. Transfusing the plasma that contains the antibodies into a person still fighting the virus can provide a boost to the patient’s immune system and potentially help them recover.
The experimental treatment is approved by the FDA to be used on an emergency basis and is called COVID-19 convalescent plasma. Patients who meet the FDA criteria can receive convalescent plasma.
OneBlood is working closely with the Florida Department of Health and directly with their hospital partners and physicians to identify people who have recovered from COVID-19 to be potential donors.
In addition to local efforts, OneBlood is also cooperating with the federal government and anticipates participating in a national-level initiative to be able to provide convalescent plasma when and where it is needed.